PROGRAM Workshop DIABETER - “Searching for a novel therapy for type 1 diabetes”

VINERI, 20 SEPTEMBRIE 2019

Aula George Emil Palade, IBPC “N. Simionescu”

15.30 -16.30 Session I: Therapeutic approaches to diabetes

15.30 -16.00 Irit Meivar Levy: “Liver to pancreas transdifferentiation; potential cell replacement therapy for Diabetes”

16.00 -16.15 Andrei Văcaru: “Reinstating self-tolerance in prediabetic mice by bone marrow transplantation”

16.15 -17.00 Alexandrina Burlacu: DIABETER Project presentation “Mesenchymal stromal cells as vectors with therapeutic potential to abrogate diabetic autoimmunity”

17.00 -18.10 Session II: Molecular design of death-inducing mesenchymal stromal cells

17.00 -17.10 Ana Văcaru: “Mesenchymal stromal cells as vectors for expression of death molecules”

17.10 -17.25 Mihai Bogdan Preda: “Remote activity of mesenchymal stromal cells in chemical diabetes”

17.25 -17.40 Anca Gafencu: “Three killer molecules: engineering adenoviruses for expression of FasL, TNFα and TRAIL”

17.40 -17.50 Mădălina Dumitrescu: “Granting killer properties to mesenchymal stromal cells by FasL- adenoviral transduction”

17.50 -18.00 Violeta Trusca: “The killing capacity of mesenchymal stromal cells -overexpressing TNFα”

18.00 -18.10 Marton Fogarasi: “Design and engineering of TRAIL-expressing mesenchymal stromal cells”

18.10 -19.00 Session III: Lessons from in vivo studies of killer MSC

18.10 -18.25 Mădălina Fenyo: “Immunomodulation of diabetic mice with killer cells”

18.25 -18.35 Ana-Maria Catrina: “Diabetic status determined by islet inflammation and insulin production in immunomodulated diabetic mice”